Mit Jai Inn was born in 1960 in Chiang Mai, northern Thailand. He is a member of the "Yong" ethnic minority. Mit became a novice monk at Djittabhawan Buddhist College, Pattaya from 1970 - 76. He began his artistic training in 1983 at Silpakorn University, Bangkok. Leaving for Europe in 1986, he enrolled in the Fine Arts Masters programme at Angewandte Kunst Wien in 1988. There, he worked as a studio assistant for Franz West from 1988–92. Returning to Thailand in 1992, he and several other artists co-founded the Chiang Mai Social Installation (CMSI). During the fourth and final edition of CMSI, Mit launched the Week of Cooperative Suffering to focus on public engagement activities.
Over the past two decades, his work has been shown in artist initiatives, museums, galleries, and mega-exhibitions, including at the Yokohama Triennale (2005); Palais de Tokyo, Paris (2007); REDCAT, Los Angeles (2007); Bangkok Art and Culture Centre (2011); Singapore Art Museum (2014); Mori Art Museum, Tokyo (2017); Kaohsiung Museum of Fine Arts (2019); Museum MACAN, Jakarta,(2019); IKON Gallery, London (2021) and at the 18th and 21st editions of the Biennale of Sydney (2012 and 2018). In 2015, Mit founded Cartel Artspace in Bangkok for artists and curators to reflect on the historical and current context of Thailand and Southeast Asia. His work is represented by Silverlens in Manila and TKG+ in Taipei. Mit lives and works in Chiang Mai.