Born in Laos, 1971, Vongpoothorn came to Australia in 1979. She completed a Bachelor of Visual Arts at the University of Western Sydney and a Masters of Fine Arts at UNSW College of Fine Arts. She has undertaken numerous residencies in Australia and overseas including in Scotland, Japan, Singapore, Vietnam and India.
She currently lives and works in Canberra. Her works are largely inspired by her own experience of being born on the banks of the Mekong River in Laos and living by the basin of the Murray River in Australia. This results in artworks that features the natural environment such as grass, vines, seeds and symbols of Buddhism.